AN23-03: Quantifying Simeticone in OTC medications with the Pearl

In this note: Quantification of the Active Pharmaceutical Product (API) in a finished product is vital to ensure the end consumer gets the correct dosage of the drug. Too little and the desired effect may not be achieved, too much and there is a risk of overdose. Fourier Transform Infrared (FTIR) spectroscopy affords a rapid cheap method for the routine testing of a wide range of pharmaceuticals when enabled by time and effort saving transmission accessories.

References

1. Simeticone – European Pharmacopoeia 10.0, 01/2017:1470
2. Bhalma et al. Nature Biomedical Engineering, 1, 0009, DOI: 10.1038/s41551-016-0009
3. Infrared and Raman Characteristic Group Frequencies, Socrates, G., John Wiley & Sons, London, Third Edition, 2001, Chapter 18, ISBN: 0470093072

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